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Personalized dosing in tuberculosis
Researchers at Radboud University Medical Center this week published results from a study in 130 patients in which they evaluated the performance of a model-based precision dosing approach (as implemented using the InsightRX Nova platform) versus current standard-of-care (a 3-sample linear-regression approach). The analysis showed that the model-based approach could achieve similar performance with less TDM samples, while also offering more flexibility in sampling times, thereby rendering the approach both a financial and a logistical improvement.
Link to study.